By no means definitive, this is a list that is based on...
1. novels
2. published between 2000 and (June) 2025
3. covering a breadth of genres and styles
4. to give a wide and deep enough feel for the time period
5. and as such just keep in mind that these aren't the "most important" or "the most popular" or "the best selling" or "the best written" etc.
6. and that includes only 1 book from any particular series
7. though a series wasn't included if the first installment published in the period is halfway or more through the series (like Pullman's Dark Materials Trilogy, with only the third of the three published during this period)