Patrick Dempsey has lived two charming but separate lives on film and television. From an exuberant, somewhat awkward charmer in college comedy films of the late 1980s and early 1990s, he has morphed spectacularly into a dreamy, wavy-haired television hunk of the new-age millennium and this seductive new image has since spilled off into romantic lead roles back on the large screen as a slightly offbeat, self-effacing Prince Charming type. Patrick Galen Dempsey was born on January 13, 1966 in Lewiston, Maine, to M. Amanda (Casson) and William Allen Dempsey. While the romantic comedy film Sweet Home Alabama (2002) opposite Reese Witherspoon really nailed the direction Dempsey was headed, the medical series Grey's Anatomy (2005), as neurosurgeon Dr. Derek Shepherd (aka "Dr. McDreamy"), gave distaff audiences the whole heartthrob package. This reawakening has also swung the door open again on high-profile film offers, notably Enchanted (2007) and Made of Honor (2008).